Shire Medical Science Liaison (MSL) Rare Diseases South Central in Remote, Texas

• Under the guidance of the MSL Lead or Country Medical Lead (CML), the Medical Science Liaison (MSL) drives the implementation of the Country medical affairs plans related primarily to KOL engagement and data dissemination.

• In a compliant manner, the MSL systematically identifies the needs of KOLs, investigators and other stakeholders in patient care, establishes strong professional relationships, provides credible scientific expertise and serves as a link to Shire Global Medical, Global Clinical and external partners.

• The MSL serves as a field-based extension of the country Therapeutic Area team.

• Externally focused, Health Care Professional (HCP) related activities are expected to comprise at least 80%of MSL responsibilities.

• The MSL maintains personal expertise in relevant disease areas and MSL best practices that can be applied externally and internally.

% of Time

Job Function and Description


KOL Engagement :

  • Through compliant scientific exchange, builds and maintains professional relationships with external stakeholders to expand Shire’s research, advisory and educational partnership opportunities

  • Ensure high standard of professionalism to develop and maintain “peer-to-peer” scientific relationships with key thought leaders in healthcare, academia, payer, and government organizations per strategic territory plans and as requested by KOLs, including the management of strategic scientific partnerships and scientific exchange

  • Provide scientific liaison support to Investigators currently involved in the Shire’s Company sponsored interventional or observational studies and investigator initiated research

  • Serve as a liaison between healthcare practitioners (HCPs) and Shire medical affairs

  • Facilitate 1:1 and group scientific interactions with healthcare professionals

  • Participate in KOL engagement planning

  • Maintain KOL plans and update medical customer relationship management system in a timely, accurate, and compliant manner


Data Dissemination

  • Contribute to compliant data dissemination according to country medical affairs plan.

  • Ensure scientific exchange with HCPs by fostering fair and balanced medical and scientific communications that are not misleading

  • Present clinical and disease state information to a variety of audiences (KOLs, HCPs, hospital/decision making teams, etc.) upon requests and/or according to country medical plans

  • Support data dissemination at congresses in according to plans

  • May be involved in responding, within defined timeline and quality standards, to unsolicited inquiries from HCPs and other stakeholders received by Global Medical Affairs and referred to GMA by other Shire functions; forwards reports of adverse events according to Shire’s policy

  • Conduct therapeutic training for Sales and Medical colleagues upon request (less than 10% of all MSL activities)

  • Other as directed by manager


Medical leadership and strategic planning

  • Communicates key medical insights from KOLs/HCPs to inform refinement of medical strategies or tactics

  • Provide scientific input and participate in local medical and cross-functional initiatives

  • Provide field-based medical support to Shire’s clinical research programs, registries, and facilitation of the investigator initiated research process

  • Participates on internal project teams as directed by Management


Knowledge, expertise and insights management

  • Maintain awareness of and access to internal and external information sources available to support high-quality scientific exchange with HCP

  • Develop/increase knowledge of medical literature and critical appraisal of scientific publications

  • Maintain knowledge base and scientific expertise on all assigned Shire disease areas and products

  • Maintaining personal expertise n MSL best practices. Develop and update knowledge of applicable pharmaceutical guidelines and regulations. Code of Ethical Practices and company policies

  • Gain customer insights, opinions and feedback and share internally

Education and Experience Requirements

  • A doctoral degree in life sciences (MD, PharmD or PhD or equivalent) is preferred; a Master’s degree in life sciences (MSN, PA-C, etc) is the minimum requirement;

  • A minimum of 2 years of either therapeutic area experience/research, or direct patient care experience

  • Experience in quickly developing a network of relationships with stakeholders to achieve business objectives

  • Experience in delivering oral presentations within the healthcare profession to both large and small audiences

  • Medical, clinical or research experience in the assigned disease area is preferred

Key Skills, Capabilities, and Competencies

  • Scientific Knowledge: Having and developing the required disease and Shire product expertise

  • Stakeholder Engagement: Ability to identify, profile, and engage in a with internal/external stakeholders, and create appropriate solutions to meet their needs

  • Medical Affairs Role expertise: Ability to execute core processes within legal, regulatory, and compliance requirements and demonstrate depth of knowledge and expertise in technical areas/systems related to role

  • Business Acumen: Ability to articulate business operations with the organization’s external environment, and how Medical Affairs practices contribute to core business functions

  • Communication: Ability to share ideas, listen, exchange information

  • Strategic Thinking: Ability to define how to move from current-state to desired- state, through the formulation of objectives and priorities—consistent with the long-term interests of the organization

  • Organizational Awareness: Ability to define, communicate and advocate the MSL role internally and externallyLearning Orientation: Ability to integrate new ideas, information and approaches, and adapt/thrive in the face of change

  • Entrepreneurial Spirit: Able to identify and pursue opportunities that generate value for the company, medical affairs, and beyond

  • Leadership Behaviors: Able to exemplify Shire’s corporate leadership behaviors

  • Be Positive

  • Be Accountable

  • Be Results Oriented

  • Be an Excellent Manager of Self and Others

  • Focus on HCP and patient needs

  • Ability to work effectively in virtual and multi-disciplinary teams

  • Highly motivated and self-directed with ability to think innovatively & strategically, skillfully plan, manage and prioritize multiple projects independently; demonstrates resilience and flexibility

  • Above average computer skills (MS Office, databases, etc)

Complexity and Problem Solving

  • Appropriate identification, assessment, and development of relationships with KOLs

  • External stakeholder management and conflict resolution

  • Individual activity plan development overseen by Manager

  • Appropriate assessment and allocation of available resources

Internal and External Contacts

  • Position is accountable to the [MSL Region or Team Lead]

  • Internal Collaboration: Global Medical Affairs, R&D, Commercial, Compliance, Legal, HR

  • External: Key opinion leaders, HCPs, patient advocacy groups, regional policy makers, etc.

Other Job Requirements

  • Frequent travel is required. Availability to travel up to 70% of time

  • Availability to attend meetings on holidays and weekends

  • Clean and valid driver’s license

  • Fluent in English and local territory language are both mandatory

Equal Employment Opportunity

Shire is an Equal Opportunity Employer committed to a diverse workforce. Shire will not discriminate against any worker or job applicant on the basis of race, color, religion, gender, national origin, ancestry, age, sexual orientation, marital or civil partnership status, pregnancy, gender reassignment, non-job related mental or physical disability, genetic information, veteran status, military service, application for military service, or membership in any other category protected under law.

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Reasonable Accommodations

Shire is committed to working with and providing reasonable accommodation to individuals with disabilities. If, because of a medical condition or disability, you need a reasonable accommodation for any part of the application process, or in order to perform the essential functions of a position, please call 484-595-8400 and let us know the nature of your request and your contact information.

Shire is the leading global biotechnology company focused on serving people with rare diseases and other highly specialized conditions. We strive to develop best-in-class products, many of which are available in more than 100 countries, across core therapeutic areas including Hematology, Immunology, Neuroscience, Ophthalmics, Lysosomal Storage Disorders, Gastrointestinal/Internal Medicine/Endocrine and Hereditary Angioedema; and a growing franchise in Oncology.

Our employees come to work every day with a shared mission: to develop and deliver breakthrough therapies for the hundreds of millions of people in the world affected by rare diseases and other high-need conditions, and who lack effective therapies to live their lives to the fullest.